Clopidogrel Hydrochloride

Preferred Label : Clopidogrel Hydrochloride;

NCIt synonyms : Clopidogrel HCl; Thieno(3,2-C)Pyridine-5(4h)-Acetic Acid, alpha-(2-Chlorophenyl)-6,7-Dihydro-, Methyl Ester, Hydrochloride, (S)-;

NCIt definition : The hydrochloride salt form of clopidogrel, a thienopyridine, with antiplatelet activity. Clopidogrel targets, irreversibly binds to and alters the platelet receptor for adenosine diphosphate (ADP), thereby blocking the binding of ADP to its receptor, inhibiting ADP-mediated activation of the glycoprotein complex GPIIb/IIIa, and inhibiting fibrinogen binding to platelets and platelet adhesion and aggregation. This results in increased bleeding time.;

UNII : 426O7XWS6Y;

InChIKey : XIHVAFJSGWDBGA-RSAXXLAASA-N;

CAS number : 120202-65-5;

Chemical formula : C16H16ClNO2S.HCl;

Details

Origin ID

C96893;

UMLS CUI

C3273104;

Automatic exact mappings (from CISMeF team)
- Clopidogrel [MeSH Descriptor]
Currated CISMeF NLP mapping
- Clopidogrel hydrochloride [SMS substance]
- Clopidogrel hydrochloride (substance) [SNOMED CT concept]
- clopidogrel hydrochloride [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Clopidogrel hydrochloride (substance) [SNOMED CT concept]
- clopidogrel hydrochloride [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
has_free_acid_or_base_form
- Clopidogrel [NCIt concept]
is_salt_form_of
- Clopidogrel [NCIt concept]

Keyword's position in hierarchy(ies) :

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