Preferred Label : Vitamin K1-containing Urea Skin Cream;
NCIt definition : A topical cream containing urea and 0.1% vitamin K1 (phytomenadione) with topical
epidermal growth factor receptor (EGFR)-activating activity. Upon application of vitamin
K1-containing urea skin cream, vitamin K1 may locally activate EGFR, thereby abrogating
EGFR inhibition in the skin caused by systemic EGFR inhibiting agents. This may help
inhibit the acne-like skin rash induced by EGFR antagonists. EGFR, a tyrosine kinase,
plays a key role in maintaining epidermal integrity.;
Drug name : Reconval K1;
NCI Metathesaurus CUI : CL429409;
Origin ID : C96802;
UMLS CUI : C3273044;
Semantic type(s)
- concept_is_in_subset
