Beta-Catenin-Activated Hepatocellular Adenoma

Preferred Label : Beta-Catenin-Activated Hepatocellular Adenoma;

NCIt synonyms : b-HCA;

NCIt definition : A hepatocellular adenoma caused by activating mutations of beta-catenin. It is characterized by the presence of nuclear atypia and absence of inflammation or steatosis. There is an increased risk of malignant transformation.;

Neoplastic status : Benign;

Details

Origin ID

C96759;

UMLS CUI

C3273009;

Disease excludes abnormal cell
- Malignant Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Disease excludes normal cell origin
- Embryonic Cell [NCIt concept]
Disease may have findings
- Fibrosis [NCIt concept]
- Hemorrhagic Change [NCIt concept]
- Necrotic Change [NCIt concept]
Excludes anatomical site(s)
- Extrahepatic Bile Duct [NCIt concept]
- Gastrointestinal Tract [NCIt concept]
Has associated anatomic sites
- Digestive System [NCIt concept]
- Hepatobiliary System [NCIt concept]
- Liver [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Inflammation [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Steatosis [NCIt concept]
disease_excludes_normal_tissue_origin
- Lymphoid Tissue [NCIt concept]
disease_has_abnormal_cell
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
disease_has_associated_disease
- Intraepithelial Neoplasia [NCIt concept]
disease_has_finding
- Benign Cellular Infiltrate [NCIt concept]
- Dysplasia [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Favorable Clinical Outcome [NCIt concept]
- Well-Circumscribed Lesion [NCIt concept]
disease_has_molecular_abnormality
- CTNNB1 Gene Mutation [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
- Glandular Cell [NCIt concept]
- Hepatocyte [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Glandular Epithelium [NCIt concept]
- Hepatic Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Digestive System [NCIt concept]
- Liver [NCIt concept]
disease_mapped_to_gene
- CTNNB1 Gene [NCIt concept]
pathogenesis_of_disease_involves_gene
- CTNNB1 Gene [NCIt concept]
- CTNNB1 wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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