HNF1alpha-Inactivated Hepatocellular Adenoma

Preferred Label : HNF1alpha-Inactivated Hepatocellular Adenoma;

NCIt synonyms : H-HCA;

NCIt definition : A hepatocellular adenoma caused by inactivating mutations of the HNF1A gene. It is characterized by the presence of lobulated contours, steatosis, and absence of inflammation or nuclear atypia.;

Neoplastic status : Benign;

Détails

Origin ID

C96758;

UMLS CUI

C3273008;

Disease excludes abnormal cell
- Malignant Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Disease excludes normal cell origin
- Embryonic Cell [NCIt concept]
Disease may have findings
- Fibrosis [NCIt concept]
- Hemorrhagic Change [NCIt concept]
- Necrotic Change [NCIt concept]
Excludes anatomical site(s)
- Extrahepatic Bile Duct [NCIt concept]
- Gastrointestinal Tract [NCIt concept]
Has associated anatomic sites
- Digestive System [NCIt concept]
- Hepatobiliary System [NCIt concept]
- Liver [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Inflammation [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
- Nuclear Atypia [NCIt concept]
disease_excludes_normal_tissue_origin
- Lymphoid Tissue [NCIt concept]
disease_has_abnormal_cell
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
disease_has_associated_disease
- Intraepithelial Neoplasia [NCIt concept]
disease_has_finding
- Benign Cellular Infiltrate [NCIt concept]
- Dysplasia [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Favorable Clinical Outcome [NCIt concept]
- Hepatic Steatosis [NCIt concept]
- Lobulated Growth Pattern [NCIt concept]
- Well-Circumscribed Lesion [NCIt concept]
disease_has_molecular_abnormality
- Inactivating HNF1A Gene Mutation [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
- Glandular Cell [NCIt concept]
- Hepatocyte [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Glandular Epithelium [NCIt concept]
- Hepatic Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Digestive System [NCIt concept]
- Liver [NCIt concept]
disease_mapped_to_gene
- HNF1A Gene [NCIt concept]
pathogenesis_of_disease_involves_gene
- HNF1A Gene [NCIt concept]
- HNF1A wt Allele [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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