Preferred Label : Lymphoma TAA-specific Cytotoxic T Lymphocytes;
NCIt definition : A population of autologous cytotoxic T lymphocytes (CTLs) with potential immunomodulating
and antitumor activities. White blood cells are grown ex-vivo and are exposed to dendritic
cells (DCs) loaded with lymphoma tumor associated antigens (TAAs); the TAA-specific
CTLs are further expanded ex-vivo before being introduced into the patient. Upon infusion
with TAA-specific CTLs, these CTLs may help activate tumor-specific CTL responses
in the patient, thereby specifically killing TAA-expressing cancer cells and eventually
inhibiting tumor cell proliferation.;
NCI Metathesaurus CUI : CL429361;
Origin ID : C96736;
UMLS CUI : C3272995;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
