Preferred Label : Ceftaroline Fosamil Acetate;
NCIt synonyms : Ceftaroline Fosamil Monoacetate Monohydrate; Ceftaroline Fosamil Monoacetate; (6R,7R)-7-(((2Z)-(Ethoxyimino)(5-(phosphonoamino)-1,2,4-thiadiazol-3-yl)acetyl)amino)-3-((4-(1-methylpyridinium-4-yl)thiazol-2-yl)sulfanyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carboxylate
Monoacetate;
NCIt definition : The acetic acid salt form of ceftaroline fosamil, an N-phosphono type prodrug of the
fifth-generation cephalosporin derivative ceftaroline with antibacterial activity.
Ceftaroline fosamil, when hydrolyzed to the active form ceftaroline, has a high affinity
for penicillin binding protein 2a (PBP2a), which is associated with methicillin resistance.
As a result, ceftaroline is unique in its activity against methicillin-resistant,
vancomycin-intermediate, linezolid-resistant, and daptomycin-nonsusceptible strains.;
UNII : P9VXV1408Y;
InChIKey : KRWPPVCZNGQQHZ-IINIBMQSSA-N;
CAS number : 400827-55-6;
Molecule name : TAK-599 Monoacetate Monohydrate; PPI-0903 Monoacetate Monohydrate;
Chemical formula : C22H21N8O8PS4.C2H4O2.H2O;
Origin ID : C96703;
UMLS CUI : C2955460;
Currated CISMeF NLP mapping
- Manual NTBT mappings (CISMeF)
- Semantic type(s)
- Validated automatic mappings to BTNT
- concept_is_in_subset
- has_free_acid_or_base_form
- is_salt_form_of
