Edoxaban - CISMeF

Preferred Label : Edoxaban;

NCIt synonyms : N-(5-chloropyridin-2-yl)-N'-[(1S,2R,4S)-4-(N,N-dimethylcarbamoyl)-2-(5-methyl-4,5,6,7- tetrahydro[1,3]thiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl]oxamide; Ethanediamide, n1-(5-chloro-2-pyridinyl)-n2-((1s,2r,4s)-4- ((dimethylamino)carbonyl)- 2-(((4,5,6,7-tetrahydro-5-methylthiazolo(5,4-c)pyridin-2-yl)carbonyl)amino)cyclohexyl)-;

NCIt definition : An orally active inhibitor of coagulation factor Xa (activated factor X) with anticoagulant activity. Edoxaban is administered as edoxaban tosylate. This agent has an elimination half-life of 9-11 hours and undergoes renal excretion.;

UNII : NDU3J18APO;

InChIKey : HGVDHZBSSITLCT-JLJPHGGASA-N;

CAS number : 480449-70-5; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 480449-70-5 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : DU-176;

Chemical formula : C24H30ClN7O4S;

Codes from synonyms : 177;

Details

Origin ID

C96539;

UMLS CUI

C2975435;

Automatic exact mappings (from CISMeF team)
- Edoxaban [ICD-11 Extension code]
- Product containing edoxaban (medicinal product) [SNOMED CT concept]
CISMeF manual mappings
- Edoxaban (substance) [SNOMED CT concept]
Currated CISMeF NLP mapping
- Edoxaban [LOINC component]
- edoxaban [MeSH concept]
- edoxaban [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Edoxaban [LOINC component]
- Edoxaban (substance) [SNOMED CT concept]
- Product containing edoxaban (medicinal product) [SNOMED CT concept]
- edoxaban [MeSH Supplementary Concept]
- edoxaban [MeSH concept]
- edoxaban [ATC Code]
Validated automatic mappings to BTNT
- edoxaban [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
has_salt_form
- Edoxaban Tosylate [NCIt concept]
is_free_acid_or_base_form_of
- Edoxaban Tosylate [NCIt concept]

Keyword's position in hierarchy(ies) :

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