DIS3 wt Allele

Preferred Label : DIS3 wt Allele;

NCIt synonyms : DKFZp667L1817; dis3p; Exosome Component 11 Gene; bA555G22.1; FLJ10484; MGC33035; KIAA1008; RP11-342J4.3; Ribosomal RNA-Processing Protein 44, S. cerevisiae, Homolog of Gene; RRP44; EXOSC11; DIS3 Mitotic Control Homolog Gene; DIS3 Homolog, Exosome Endoribonuclease and 3-Prime-5-Prime Exoribonuclease Gene; 2810028N01Rik; DIS3 Homolog, Exosome Endoribonuclease and 3'-5' Exoribonuclease wt Allele; DIS3 Mitotic Control, S. cerevisiae, Homolog of Gene; DIS3 Mitotic Control Homolog (S. cerevisiae) Gene;

NCIt definition : Human DIS3 wild-type allele is located in the vicinity of 13q22.1 and is approximately 27 kb in length. This allele, which encodes exosome complex exonuclease RRP44 protein, plays a role in the modulation of ribosomal RNA processing.;

NCIt note : Mutations in the protein-coding region of the DIS3 gene were found in multiple myeloma. (Nature. 2011; 471: 467-472.);

GenBank Accession Number : AB023225;

Details

Origin ID

C96359;

UMLS CUI

C3272733;

OMIM relation
- Dis3 homolog, exosome endoribonuclease and 3-prime-5-prime exoribonuclease [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_is_element_in_pathway
- RNA Degradation Pathway [NCIt concept]
gene_plays_role_in_process
- Hydrolysis [NCIt concept]
- RNA Degradation [NCIt concept]
- RNA Processing [NCIt concept]

Keyword's position in hierarchy(ies) :

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