Preferred Label : 18-F-fluoroacetate;
NCIt synonyms : Fluorine F 18 Fluoroacetate; (18)F-FAC;
NCIt definition : A radioconjugate and an acetate analog labeled with fluorine F 18 ((18)F-FAC), a positron-emitting
isotope, with potential prostate tumor tracer property using positron emission tomography
(PET). Although the mechanism of action is unclear, fluorine F 18 acetate preferentially
accumulates in tumor tissue, serving as a tracer for imaging tumors with PET. Fluorine
18 has a longer radioactive half-life (110 min) vs. the half-life of carbon-11 acetate
(20.4 min). Furthermore, (18)F-FAC showed a rapid clearance from liver and extensive
excretion to bile and urine in comparison with carbon-11 acetate, therefore this tracer
may be a useful alternative to C-11 acetate for the detection of prostate tumors by
PET.;
NCI Metathesaurus CUI : CL429016;
Origin ID : C96236;
UMLS CUI : C3272664;
Semantic type(s)
- concept_is_in_subset
