Preferred Label : Muscadine Grape Skin Extract;
NCIt synonyms : MSKE;
NCIt definition : A nutritional supplement containing an extract of the skin of Muscadine grape (Vitis
rotundifolia), with anti-inflammatory, antioxidant and potential chemopreventive activities.
The skin extract of the muscadine grape contains numerous phytochemicals including
hydrolyzable tannins and flavonoids, such as anthocyanin 3,5-diglucosides, quercetin,
myricetin, and kaempferol glycosides. Upon administration, muscadine grape skin extract
(MSKE) appears to inhibit PI3K/Akt and MAPK signaling, eventually leading to apoptosis
and a reduction in tumor cell proliferation.;
NCI Metathesaurus CUI : CL429013;
Origin ID : C96231;
UMLS CUI : C3272661;
Semantic type(s)
- concept_is_in_subset
