Colorectal Large Cell Neuroendocrine Carcinoma

Preferred Label : Colorectal Large Cell Neuroendocrine Carcinoma;

NCIt synonyms : Large Intestinal Large Cell Neuroendocrine Carcinoma;

NCIt definition : An aggressive, high-grade, and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the colon or rectum. It is characterized by the presence of malignant large cells.;

Neoplastic status : Malignant;

Details

Origin ID

C96157;

UMLS CUI

C3272608;

Currated CISMeF NLP mapping
- large cell neuroendocrine colorectal carcinoma [Disease (Nov.)]
Disease excludes abnormal cell
- Large Osteoclastic Giant Cell [NCIt concept]
- Malignant Neuroendocrine Small Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Disease may have findings
- Aggressive Clinical Course [NCIt concept]
- Neuron-Specific Enolase Positive Neoplastic Cells Present [NCIt concept]
Excludes anatomical site(s)
- Head and Neck [NCIt concept]
- Lung [NCIt concept]
Has associated anatomic sites
- Colorectal Region [NCIt concept]
- Digestive System [NCIt concept]
- Intestine [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- large cell neuroendocrine colorectal carcinoma [Disease (Nov.)]
concept_is_in_subset
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Glandular Differentiation [NCIt concept]
- Intermediate Grade Neuroendocrine Lesion [NCIt concept]
- Low Grade Neuroendocrine Lesion [NCIt concept]
- Low Mitotic Activity [NCIt concept]
- Squamous Differentiation [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Endocrine Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Epithelial Large Cell [NCIt concept]
- Malignant Neuroendocrine Cell [NCIt concept]
- Malignant Neuroendocrine Large Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Endocrine Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Neuroendocrine Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Endocrine Differentiation [NCIt concept]
- Epithelial Component Present [NCIt concept]
- High Mitotic Activity [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Necrotic Change [NCIt concept]
- Neuroendocrine Differentiation [NCIt concept]
- Poorly Differentiated Neuroendocrine Lesion [NCIt concept]
- Severe Cytologic Atypia [NCIt concept]
disease_has_grade
- Grade 3 [NCIt concept]
- High Grade [NCIt concept]
disease_has_normal_cell_origin
- Endocrine Cell of the Digestive System [NCIt concept]
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Large Intestinal Mucosa [NCIt concept]
disease_has_primary_anatomic_site
- Colorectal Region [NCIt concept]
- Digestive System [NCIt concept]
- Intestine [NCIt concept]
disease_mapped_to_gene
- APC Gene [NCIt concept]
- BRAF Gene [NCIt concept]
- KRAS Gene [NCIt concept]
- TP53 Gene [NCIt concept]
disease_may_have_molecular_abnormality
- BRAF Gene Mutation [NCIt concept]
- Inactivating APC Gene Mutation [NCIt concept]
- KRAS Gene Amplification [NCIt concept]
- MYC Gene Mutation [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]

Keyword's position in hierarchy(ies) :

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