Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma

Preferred Label : Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma;

NCIt synonyms : Type II EATL; MEITL; Monomorphic CD56 Intestinal T-Cell Lymphoma;

NCIt definition : A mature T-cell and NK-cell non-Hodgkin lymphoma of intraepithelial T-lymphocytes. It usually arises from the small intestine. A minority of cases arise from the large intestine or the stomach. It is characterized by the presence of a monomorphic cellular infiltrate of small to medium-sized T-lymphocytes that are cytotoxic and express CD56. It is not associated with celiac disease.;

Neoplastic status : Malignant;

Details

Origin ID

C96058;

UMLS CUI

C3272525;

Automatic exact mappings (from CISMeF team)
- Monomorphic epitheliotropic intestinal T-cell lymphoma [ICD-11 Extension code]
Currated CISMeF NLP mapping
- Monomorphic epitheliotropic intestinal T-cell lymphoma (morphologic abnormality) [SNOMED CT concept]
Disease excludes abnormal cell
- Lymphocyte Predominant Cell [NCIt concept]
- Neoplastic B-Lymphocyte [NCIt concept]
- Reed-Sternberg Cell [NCIt concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Plasma Cell [NCIt concept]
- Precursor Natural Killer Cell [NCIt concept]
- Precursor T-Lymphoblast [NCIt concept]
Disease may have findings
- Aggressive Clinical Course [NCIt concept]
- SETD2 Gene Alteration Positive [NCIt concept]
Has associated anatomic sites
- Digestive System [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
- Intestine [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Monomorphic epitheliotropic intestinal T-cell lymphoma (morphologic abnormality) [SNOMED CT concept]
concept_is_in_subset
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
- Neoplastic Small to Medium-Sized T-Lymphocyte [NCIt concept]
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
disease_has_finding
- CD56-Positive Neoplastic Cells Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Monomorphic Cellular Infiltrate [NCIt concept]
disease_has_molecular_abnormality
- Clonal T-Cell Receptor Beta Chain Gene Rearrangement [NCIt concept]
- Clonal T-Cell Receptor Gamma Chain Gene Rearrangement [NCIt concept]
disease_has_normal_cell_origin
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Intraepithelial T-Lymphocyte [NCIt concept]
- Lymphocyte [NCIt concept]
- Peripheral (Post-Thymic) T-Lymphocyte and Natural Killer Cell [NCIt concept]
- T-Lymphocyte and Natural Killer Cell [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Digestive System [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
disease_may_have_molecular_abnormality
- JAK3 Gene Mutation [NCIt concept]
- SETD2 Gene Deletion [NCIt concept]
- SETD2 Gene Mutation [NCIt concept]
- STAT5B Gene Mutation [NCIt concept]
- TP53 Gene Mutation [NCIt concept]

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