CIITA wt Allele

Preferred Label : CIITA wt Allele;

NCIt synonyms : MHC Class II Transactivator Gene; Nucleotide-Binding Oligomerization Domain, Leucine Rich Repeat and Acid Domain Containing Gene; Class II Major Histocompatibility Complex Transactivator wt Allele; MHC2TA; CIITAIV; C2TA; NLRA; NLR Family, Acid Domain Containing Gene; Major Histocompatibility Complex, Class II, Transactivator Gene; Class II, Major Histocompatibility Complex, Transactivator Gene;

NCIt definition : Human CIITA wild-type allele is located in the vicinity of 16p13 and is approximately 48 kb in length. This allele, which encodes MHC class II transactivator protein, is involved in the modulation of MHC class II gene expression.;

NCIt note : Genetic aberrations involving the CITTA gene may be associated with lymphoid cancers. (Nature 2011; doi:10.1038/nature09754.);

GenBank Accession Number : U18259;

Details

Origin ID

C96014;

UMLS CUI

C3272496;

OMIM relation
- Class II major histocompatibility complex transactivator [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_is_element_in_pathway
- Antigen Processing and Presentation Pathway [NCIt concept]
- Primary Immunodeficiency Pathway [NCIt concept]
gene_plays_role_in_process
- Antigen Presentation [NCIt concept]
- Interferon Signaling Process [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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