Ampulla of Vater Neuroendocrine Carcinoma

Preferred Label : Ampulla of Vater Neuroendocrine Carcinoma;

NCIt synonyms : Ampulla of Vater NEC; Ampulla of Vater Poorly Differentiated Endocrine Carcinoma; Ampulla of Vater High Grade Neuroendocrine Carcinoma; Ampulla of Vater NEC G3; Neuroendocrine Carcinoma of the Ampullary Region; Ampulla of Vater Small and Large Cell Endocrine Carcinoma;

NCIt definition : An aggressive, high-grade, and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the ampulla of Vater. The mitotic count is more than 20 per 10 HPF. It is classified as either small or large cell neuroendocrine carcinoma based on the size of the malignant cells, the prominence of the nucleoli, and the amount of cytoplasm.;

Neoplastic status : Malignant;

Details

Origin ID

C95984;

UMLS CUI

C3272480;

Automatic exact mappings (from CISMeF team)
- Neuroendocrine neoplasms of ampulla of Vater [ICD-11 Subcategory]
Disease excludes abnormal cell
- Large Osteoclastic Giant Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Excludes anatomical site(s)
- Head and Neck [NCIt concept]
- Lung [NCIt concept]
Has associated anatomic sites
- Ampulla of Vater [NCIt concept]
- Digestive System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Intermediate Grade Neuroendocrine Lesion [NCIt concept]
- Low Grade Neuroendocrine Lesion [NCIt concept]
- Low Mitotic Activity [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Endocrine Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Neuroendocrine Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Endocrine Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Neuroendocrine Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Endocrine Differentiation [NCIt concept]
- Epithelial Component Present [NCIt concept]
- High Mitotic Activity [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Neuroendocrine Differentiation [NCIt concept]
- Poorly Differentiated Neuroendocrine Lesion [NCIt concept]
- Severe Cytologic Atypia [NCIt concept]
disease_has_grade
- Grade 3 [NCIt concept]
- High Grade [NCIt concept]
disease_has_normal_cell_origin
- Endocrine Cell of the Digestive System [NCIt concept]
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Ampulla of Vater [NCIt concept]
- Digestive System [NCIt concept]
- Pancreatobiliary System [NCIt concept]

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