Ampulla of Vater Hepatoid Adenocarcinoma

Preferred Label : Ampulla of Vater Hepatoid Adenocarcinoma;

NCIt definition : A very rare adenocarcinoma that arises from the ampulla of Vater. It is usually of the intestinal type and is characterized by the presence of malignant polygonal cells with abundant eosinophilic cytoplasm resembling hepatocytes.;

Neoplastic status : Malignant;

Details

Origin ID

C95966;

UMLS CUI

C3272464;

Disease excludes abnormal cell
- Malignant Squamous Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Disease may have findings
- Abdominal Pain [NCIt concept]
- Anorexia [NCIt concept]
- Jaundice [NCIt concept]
- Lower Gastrointestinal Hemorrhage [NCIt concept]
- Malaise [NCIt concept]
- Nausea [NCIt concept]
- Pruritus [NCIt concept]
- Vomiting [NCIt concept]
- Weight Loss [NCIt concept]
Excludes anatomical site(s)
- Liver [NCIt concept]
Has associated anatomic sites
- Ampulla of Vater [NCIt concept]
- Digestive System [NCIt concept]
- Intestine [NCIt concept]
- Small Intestine [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
concept_is_in_subset
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Intermediate Grade Neuroendocrine Lesion [NCIt concept]
- Low Grade Neuroendocrine Lesion [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_abnormal_cell
- Adenocarcinoma Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
- Polygonal Adenocarcinoma Cell with Eosinophilic Cytoplasm [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
- Glandular Cell [NCIt concept]
- Small Intestinal Glandular Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Glandular Epithelium [NCIt concept]
- Small Intestinal Mucosa [NCIt concept]
disease_has_primary_anatomic_site
- Ampulla of Vater [NCIt concept]
- Digestive System [NCIt concept]
- Small Intestine [NCIt concept]
disease_mapped_to_gene
- KRAS Gene [NCIt concept]
- SMAD4 Gene [NCIt concept]
- TP53 Gene [NCIt concept]
disease_may_have_associated_disease
- Crohn Disease [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Loss of Chromosome 17p [NCIt concept]
- Loss of Chromosome 18q [NCIt concept]
- Loss of Chromosome 5q [NCIt concept]
disease_may_have_molecular_abnormality
- CTNNB1 Gene Mutation [NCIt concept]
- KRAS Gene Mutation [NCIt concept]
- Loss of E-cadherin Expression [NCIt concept]
- Microsatellite Instability [NCIt concept]
- SMAD4 Gene Inactivation [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]

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