" /> Mavrilimumab - CISMeF





Preferred Label : Mavrilimumab;

NCIt synonyms : Immunoglobulin G4, Anti-(Human Granulocyte-Macrophage Colony-Stimulating-Factor Receptor alpha-Chain) (Human Monoclonal CAM-3001 Heavy Chain), Disulfide with Human Monoclonal CAM-3001 lambda-Chain, Dimer;

NCIt definition : A human IgG4 monoclonal antibody targeting the alpha chain of the granulocyte-macrophage colony-stimulating factor receptor (GM-CSF-Ra), with potential immunomodulating activity. Mavrilimumab binds to GM-CSF-Ra and inhibits the GM-CSF-mediated pathway. This may inhibit inflammation. GM-CSF and its receptor are upregulated in a number of autoimmune diseases and play a key role in the activation, differentiation and function of both granulocytes and monocytes.;

UNII : 1158JD1P9A;

CAS number : 1085337-57-0;

Molecule name : CAM-3001;

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31/07/2025


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