Preferred Label : Primary Prostate Cancer Tissue/hTERT/Survivin mRNA-loaded Autologous Dendritic Cell
Vaccine;
NCIt definition : An autologous dendritic cells (DCs) vaccine targeting prostate cancer with immunostimulating
activity. The autologous DC vaccine is prepared via transfecting DCs with mRNAs extracted
from primary prostate cancer tissue, and mRNAs of human telomerase reverse transcriptase
(hTERT) and survivin. Upon administration, this DC vaccine may elicit a potent cytotoxic
T-cell (CTL) response against prostate cancer cells, resulting in tumor cell death.
Both hTERT and survivin are essential in neoplastic growth, and are considered to
be universal tumor antigens.;
NCI Metathesaurus CUI : CL428213;
Origin ID : C95771;
UMLS CUI : C2987412;
Semantic type(s)
- concept_is_in_subset
