Preferred Label : MELITAC 12.1 Peptide Vaccine;
NCIt definition : A peptide cancer vaccine consisting of an emulsion of a mixture of 12 class I MHC-restricted
melanoma peptides and a class II MHC-restricted tetanus toxoid helper peptide, with
potential immunostimulating and antineoplastic activities. Upon administration, the
MELITAC 12.1 peptide vaccine may stimulate the host immune system to mount a cytotoxic
T-cell response against tumor cells expressing the melanoma peptide antigens, resulting
in tumor cell lysis. The melanoma peptides contained in the vaccine are upregulated
in melanoma cancer cells.;
NCI Metathesaurus CUI : CL428198;
Origin ID : C95741;
UMLS CUI : C2987391;
Semantic type(s)
- chemical_or_drug_has_mechanism_of_action
- concept_is_in_subset
