" /> Lucitanib - CISMeF





Preferred Label : Lucitanib;

NCIt synonyms : 1-Naphthalenecarboxamide, 6-((7-((1-aminocyclopropyl)methoxy)-6-methoxy-4-quinolinyl)oxy)-n-methyl-;

NCIt definition : A novel dual inhibitor targeting human vascular endothelial growth factor receptors (VEGFRs) and fibroblast growth factor receptors (FGFRs) with antiangiogenic activity. Lucitanib inhibits VEGFR-1, -2, -3 and FGFR-1, -2 kinases in the nM range, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation, and the induction of tumor cell death. Both VEGFRs and FGFRs belong to the family of receptor tyrosine kinases that may be upregulated in various tumor cell types.;

UNII : PP449XA4BH;

InChIKey : CUDVHEFYRIWYQD-UHFFFAOYSA-N;

CAS number : 1058137-23-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1058137-23-7 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : E-3810; AL3810;

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Keyword's position in hierarchy(ies) : arborescence

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12/05/2024


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