Preferred Label : Timolol Maleate Gel Forming Solution;
NCIt synonyms : (-)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-2-propanol Maleate
(1:1) (Salt);
NCIt definition : A gel forming solution containing the maleate salt of timolol, a propanolamine derivative
and a non-selective beta-adrenergic antagonist, with intraocular pressure-reducing
activity. Although the precise mechanism of action of timolol's ocular hypotensive
action is not clearly established at this time, studies suggest that it may be the
result of decreased aqueous humor production (possibly by reduction of blood flow
to the ciliary processes and cAMP synthesis) as well as a slight increase in outflow
facility. Timolol gel-forming solution can potentially be used topically as well,
in the prevention of the neoangiogenesis that may occur following pulsed dye laser
treatment of port wine stains.;
Drug name : Timoptic-XE;
Origin ID : C95714;
UMLS CUI : C2987367;
Semantic type(s)
concept_is_in_subset