Antibiotic SQ109

Preferred Label : Antibiotic SQ109;

NCIt synonyms : N-Geranyl-N'-(2-adamantyl)ethane-1,2-diamine;

NCIt related terms : SQ-109;

NCIt definition : An orally available, acid-stable diamine antibiotic, with potential antimicrobial activity against a variety of bacteria including Helicobacter pylori (H. pylori) and Mycobacterium tuberculosis (M. Tuberculosis). As an ethambutol analogue with asymmetric structure, SQ109 does not act on the same target as ethambutol. However, this agent interferes with cell wall synthesis, thereby causing weakening of the cell wall and ultimately cell lysis.;

UNII : 9AU7XUV31A;

CAS number : 502487-67-4;

Molecule name : SQ109;

PubMed : 20385864;

Details

Origin ID

C95706;

UMLS CUI

C1688515;

Currated CISMeF NLP mapping
- N-adamantanyl-n'-geranyl-ethylenediamine [SMS substance]
- N-geranyl-N'-(2-adamantyl)ethane-1,2-diamine [MeSH concept]
- N-geranyl-N'-(2-adamantyl)ethane-1,2-diamine [MeSH Supplementary Concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- N-geranyl-N'-(2-adamantyl)ethane-1,2-diamine [MeSH concept]
- N-geranyl-N'-(2-adamantyl)ethane-1,2-diamine [MeSH Supplementary Concept]
- SQ 109 [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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