Pancreatic Gastrinoma

Preferred Label : Pancreatic Gastrinoma;

NCIt definition : A neuroendocrine tumor arising from the pancreas. It is characterized by inappropriate secretion of gastrin and associated with Zollinger Ellison syndrome. The latter is characterized by the presence of peptic ulcer, gastroesophageal reflux disease, abdominal pain, diarrhea, and malabsorption.;

Neoplastic status : Undetermined;

Details

Origin ID

C95596;

UMLS CUI

C5848106;

Currated CISMeF NLP mapping
- pancreatic gastrinoma [DO Concept]
- pancreatic gastrinoma [Disease (Nov.)]
Disease excludes abnormal cell
- Large Osteoclastic Giant Cell [NCIt concept]
- Neoplastic Endothelial Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Disease excludes normal cell origin
- Endothelial Cell [NCIt concept]
Has associated anatomic sites
- Digestive System [NCIt concept]
- Pancreas [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- pancreatic gastrinoma [DO Concept]
- pancreatic gastrinoma [Disease (Nov.)]
disease_excludes_finding
- Absence of a Hormonal Syndrome [NCIt concept]
- High Mitotic Activity [NCIt concept]
- Poorly Differentiated Neuroendocrine Lesion [NCIt concept]
- Severe Cytologic Atypia [NCIt concept]
disease_has_abnormal_cell
- Neoplastic Cell [NCIt concept]
- Neoplastic Endocrine Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Neuroendocrine Cell [NCIt concept]
disease_has_associated_disease
- Zollinger Ellison Syndrome [NCIt concept]
disease_has_finding
- Endocrine Differentiation [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Expression of Neuroendocrine Markers Present [NCIt concept]
- Gastrin-Positive Neoplastic Cells Present [NCIt concept]
- Gyriform Trabecular Pattern [NCIt concept]
- Low Mitotic Activity [NCIt concept]
- Neuroendocrine Differentiation [NCIt concept]
- Presence of a Hormonal Syndrome [NCIt concept]
- Pseudorosette Formation [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_normal_cell_origin
- Endocrine Cell of the Digestive System [NCIt concept]
- Epithelial Cell [NCIt concept]
- Islet Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Islet of Langerhans [NCIt concept]
disease_has_primary_anatomic_site
- Digestive System [NCIt concept]
- Islet of Langerhans [NCIt concept]
- Pancreas [NCIt concept]
disease_mapped_to_gene
- MEN1 Gene [NCIt concept]
- VHL Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Loss of Chromosome 3p [NCIt concept]
- del(18q21) [NCIt concept]

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