Pancreatic Poorly Differentiated Ductal Adenocarcinoma

Preferred Label : Pancreatic Poorly Differentiated Ductal Adenocarcinoma;

NCIt definition : A pancreatic ductal adenocarcinoma characterized by the presence of small and irregular malignant glandular structures, solid sheets of malignant cells, and single malignant cells.;

Neoplastic status : Malignant;

Details

Origin ID

C95428;

UMLS CUI

C2987141;

Disease excludes abnormal cell
- Malignant Neuroendocrine Cell [NCIt concept]
- Malignant Squamous Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
- Secretory Adenocarcinoma Cell [NCIt concept]
Disease may have findings
- Abdominal Pain [NCIt concept]
- Jaundice [NCIt concept]
- Pruritus [NCIt concept]
- Weight Loss [NCIt concept]
Has associated anatomic sites
- Digestive System [NCIt concept]
- Pancreas [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Acinar Cell Differentiation [NCIt concept]
- Benign Cellular Infiltrate [NCIt concept]
- Intermediate Grade Neuroendocrine Lesion [NCIt concept]
- Low Grade Neuroendocrine Lesion [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
- Syncytial Pattern [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_abnormal_cell
- Adenocarcinoma Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Fibrotic Stroma Formation [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Poorly Differentiated Lesion [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
- Glandular Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Glandular Epithelium [NCIt concept]
disease_has_primary_anatomic_site
- Digestive System [NCIt concept]
- Exocrine Pancreas [NCIt concept]
- Pancreatic Duct [NCIt concept]
- Pancreatobiliary System [NCIt concept]
disease_mapped_to_gene
- BRCA2 Gene [NCIt concept]
- CDKN2A Gene [NCIt concept]
- ERBB2 Gene [NCIt concept]
- KRAS Gene [NCIt concept]
- SMAD4 Gene [NCIt concept]
- TP53 Gene [NCIt concept]
disease_may_have_associated_disease
- Diabetes Mellitus [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 12 [NCIt concept]
- Gain of Chromosome 7 [NCIt concept]
- Loss of Chromosome 12 [NCIt concept]
- Loss of Chromosome 13 [NCIt concept]
- Loss of Chromosome 17 [NCIt concept]
- Loss of Chromosome 18 [NCIt concept]
- Loss of Chromosome 1p [NCIt concept]
- Loss of Chromosome 3p [NCIt concept]
- Loss of Chromosome 6 [NCIt concept]
- Loss of Chromosome 8p [NCIt concept]
- Loss of Chromosome 9p [NCIt concept]
disease_may_have_molecular_abnormality
- AKT2 Gene Amplification [NCIt concept]
- BRCA2 Gene Mutation [NCIt concept]
- CDKN2A Gene Inactivation [NCIt concept]
- ERBB2 Gene Amplification [NCIt concept]
- KRAS Gene Mutation [NCIt concept]
- MAP2K4 Gene Inactivation [NCIt concept]
- RB1 Gene Inactivation [NCIt concept]
- SMAD4 Gene Inactivation [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]

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