Tauromustine - CISMeF

Preferred Label : Tauromustine;

NCIt synonyms : 1-(2-Chloroethyl)-3-(2-(dimethylaminosulfonyl)ethyl)-1-nitrosourea; TCNU;

NCIt definition : A water-soluble taurine-based nitrosourea with potential antineoplastic activity. Tauromustine alkylates DNA and causes DNA cross links independent of cell cycle, thereby resulting in disruption of DNA function and induction of apoptosis.;

UNII : 511F69K76Y;

InChIKey : RCLLNBVPCJDIPX-UHFFFAOYSA-N;

CAS number : 85977-49-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 85977-49-7 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : LS-2667;

Chemical formula : C7H15ClN4O4S;

Details

Origin ID

C954;

UMLS CUI

C0044133;

Automatic exact mappings (from CISMeF team)
- Tauromustine [ICHI extension code]
Currated CISMeF NLP mapping
- 1-(2-chloroethyl)-3-(2-(dimethylaminosulfonyl)ethyl)-1-nitrosourea [MeSH concept]
- 1-(2-chloroethyl)-3-(2-(dimethylaminosulfonyl)ethyl)-1-nitrosourea [MeSH Supplementary Concept]
- Tauromustine [ICD-11 Extension code]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- 1-(2-chloroethyl)-3-(2-(dimethylaminosulfonyl)ethyl)-1-nitrosourea [MeSH Supplementary Concept]
- 1-(2-chloroethyl)-3-(2-(dimethylaminosulfonyl)ethyl)-1-nitrosourea [MeSH concept]
- Tauromustine [ICD-11 Extension code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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