TET2 wt Allele

Preferred Label : TET2 wt Allele;

NCIt synonyms : KIAA1546; Tet Methylcytosine Dioxygenase 2 wt Allele; FLJ20032; MGC125715; Tet Oncogene Family Member 2 Gene;

NCIt definition : Human TET2 wild-type allele is located in the vicinity of 4q24 and is approximately 134 kb in length. This allele, which encodes methylcytosine dioxygenase TET2 protein, plays a role in cytosine metabolism. Mutation of the gene is associated with myeloproliferative disorders, polycythemia vera, systemic mastocytosis and myelodysplastic syndromes.;

GenBank Accession Number : AB046766;

Details

Origin ID

C95253;

UMLS CUI

C2987021;

OMIM relation
- Tet methylcytosine dioxygenase 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- Polycythemia Vera [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- ST2 Diffuse Large B-Cell Lymphoma [NCIt concept]
gene_plays_role_in_process
- Cell Cycle Regulation Process [NCIt concept]
- DNA Methylation Regulation [NCIt concept]
- Myelopoiesis [NCIt concept]
- Nucleotide Metabolic Process [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- Tumor Suppression [NCIt concept]

Keyword's position in hierarchy(ies) :

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