GLRX3 wt Allele

Preferred Label : GLRX3 wt Allele;

NCIt synonyms : FLJ11864; GRX4; Glutaredoxin 3 wt Allele; HUSSY-22; Glutaredoxin 4 Gene; TXNL3; Thioredoxin-Like 2 Gene; TXNL2; PICOT; GRX3;

NCIt definition : Human GLRX3 wild-type allele is located in the vicinity of 10q26 and is approximately 48 kb in length. This allele, which encodes glutaredoxin-3 protein, plays a role in cardiac maintenance and cellular redox.;

NCIt note : Aberrant expression of the human GLRX3 gene in cancer cells may protect them from oxidative stress. (J Clin Invest. 2011; 121: 212-225.);

GenBank Accession Number : AJ010841;

Details

Origin ID

C95247;

UMLS CUI

C2987019;

OMIM relation
- Glutaredoxin 3 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 10q26 [NCIt concept]
gene_plays_role_in_process
- Homeostatic Process [NCIt concept]
- Oxidation/Reduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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