NCIt definition : The potassium salt of a narrow-spectrum, semisynthetic penicillin derivative with
antibacterial activity. Azidocillin binds to and inactivates penicillin-binding proteins
(PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs
interferes with the cross-linkage of peptidoglycan chains necessary for bacterial
cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and
results in the weakening of the bacterial cell wall, eventually causing cell lysis.;