NCIt definition : Malignant neoplasms occurring in families at a rate greater than that expected by
chance and caused by germline mutations in a specific gene.;
Alternative definition : NCI-GLOSS: Cancer that occurs in families more often than would be expected by chance.
These cancers often occur at an early age, and may indicate the presence of a gene
mutation that increases the risk of cancer. They may also be a sign of shared environmental
or lifestyle factors.;
Semantic type(s)