Breast Ductal Carcinoma In Situ, Intermediate Grade

Preferred Label : Breast Ductal Carcinoma In Situ, Intermediate Grade;

NCIt synonyms : DCIS Grade 2; Intermediate-Grade Ductal Carcinoma In Situ of Breast; Intermediate-Grade DCIS; Ductal Intraepithelial Neoplasia, Grade 2; DIN 2; Intermediate-Grade Ductal Carcinoma In Situ of the Breast; Intermediate Grade Ductal Breast Carcinoma In Situ;

NCIt definition : Breast ductal carcinoma in situ characterized by the presence of monomorphic neoplastic cells that form cribriform, micropapillary, or solid patterns. Intraluminal necrosis is present in some ducts. Ducts that contain neoplastic cells with occasional nucleoli and coarse chromatin may also be present.;

Neoplastic status : Malignant;

Details

Origin ID

C9456;

UMLS CUI

C1334206;

Disease excludes abnormal cell
- Dysplastic Squamous Cell [NCIt concept]
- Malignant Squamous Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Disease may have findings
- Calcification [NCIt concept]
- Cribriform Pattern [NCIt concept]
- Microcalcification [NCIt concept]
- Micropapillary Growth Pattern [NCIt concept]
- Solid Growth Pattern [NCIt concept]
Has associated anatomic sites
- Breast [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Invasive Lesion [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
disease_excludes_molecular_abnormality
- CDH1 Gene Inactivation [NCIt concept]
- Loss of E-cadherin Expression [NCIt concept]
disease_has_abnormal_cell
- Adenocarcinoma Cell [NCIt concept]
- Ductal Carcinoma Cell [NCIt concept]
- Dysplastic Glandular Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
- Round Adenocarcinoma Cell [NCIt concept]
disease_has_finding
- Absence of Invasion [NCIt concept]
- Carcinomatous Component Present [NCIt concept]
- Dysplasia [NCIt concept]
- Epithelial Component Present [NCIt concept]
- In Situ Lesion [NCIt concept]
- Intraductal Cellular Proliferation [NCIt concept]
- Intraductal Lesion [NCIt concept]
- Intraluminal Necrosis [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Severe Dysplasia [NCIt concept]
disease_has_grade
- Grade 3 [NCIt concept]
- High Grade [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
- Glandular Cell [NCIt concept]
- Terminal Ductal Lobular Unit Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Glandular Epithelium [NCIt concept]
- Mammary Epithelium [NCIt concept]
- Terminal Ductal Lobular Unit [NCIt concept]
disease_has_primary_anatomic_site
- Breast [NCIt concept]
disease_is_stage
- AJCC v6 Stage [NCIt concept]
- AJCC v7 Stage [NCIt concept]
- AJCC v8 Stage [NCIt concept]
- Breast Cancer Anatomic Stage [NCIt concept]
- Stage 0 [NCIt concept]
disease_mapped_to_gene
- CCND1 Gene [NCIt concept]
- ERBB2 Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Loss of Chromosome 1 [NCIt concept]
- Loss of Chromosome 18 [NCIt concept]
- Polysomy 10 [NCIt concept]
- Polysomy 17 [NCIt concept]
- Polysomy 3 [NCIt concept]
disease_may_have_molecular_abnormality
- CCND1 Gene Amplification [NCIt concept]
- CCND1 Protein Overexpression [NCIt concept]
- Cyclin D1 Messenger RNA Overexpression [NCIt concept]
- ERBB2 Gene Amplification [NCIt concept]
- ERBB2 Protein Overexpression [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]

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