Spindle Cell Oncocytoma

Preferred Label : Spindle Cell Oncocytoma;

NCIt synonyms : Spindle Cell Oncocytoma of the Adenohypophysis (WHO Grade 1); Folliculo-Stellate Cell Tumor of the Pituitary; SCO; Spindle Cell Oncocytoma of the Adenohypophysis; Spindle Cell Oncocytoma/Oncocytic Pituicytoma; Pituitary Gland Oncocytoma;

NCIt definition : A very rare, WHO grade 1 neoplasm of the posterior pituitary. It is characterized by the presence of spindle cells with eosinophilic, granular cytoplasm forming fascicles. Electron microscopic studies demonstrate the accumulation of intracytoplasmic mitochondria and lack of secretory granules. Immunohistochemical studies are negative for pituitary hormones. Patients may present with pituitary hypofunction, visual disturbances, headache, nausea and vomiting. The clinical course is usually benign.;

Neoplastic status : Undetermined;

ICD-O code : 8290/0;

Details

Origin ID

C94537;

UMLS CUI

C2986561;

Disease excludes abnormal cell
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Excludes anatomical site(s)
- Spinal Cord [NCIt concept]
Has associated anatomic sites
- Base of the Skull [NCIt concept]
- Central Nervous System [NCIt concept]
- Head and Neck [NCIt concept]
- Nervous System [NCIt concept]
- Pituitary Gland [NCIt concept]
- Sellar Region [NCIt concept]
- Skull [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Spindle cell oncocytoma (morphologic abnormality) [SNOMED CT concept]
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- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
disease_excludes_finding
- Aggressive Clinical Course [NCIt concept]
- Metastatic Lesion [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
disease_has_abnormal_cell
- Neoplastic Cell [NCIt concept]
- Neoplastic Eosinophilic Spindle Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
- Neoplastic Oncocyte [NCIt concept]
disease_has_finding
- Epithelial Component Present [NCIt concept]
disease_has_grade
- Grade 1 [NCIt concept]
- Low Grade [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
- Pituicyte [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Central Nervous System [NCIt concept]
- Posterior Lobe of the Pituitary Gland [NCIt concept]

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