Technetium Tc-99m Hydroxydiphosphonate

Preferred Label : Technetium Tc-99m Hydroxydiphosphonate;

NCIt synonyms : Tc-99m Hydroxydiphosphonate; 99mTc HDP;

NCIt definition : A radioconjugate containing hydroxydiphosphonate (HDP) labeled with the metastable radioisotope technetium Tc (99mTc), with radioimaging activity. Upon intravenous administration, skeletal uptake of technetium Tc-99m HDP occurs as a function of skeletal blood flow and osteogenic activity. HDP has a specific affinity for hydroxyapatite crystals in bone where abnormal accumulation of increased osteoid mineralization has occurred. Labeling of HDP with 99mTc allows gamma scintigraphic imaging of areas of abnormal osteogenesis associated with malignant bone lesions.;

Details

Origin ID

C94222;

UMLS CUI

C0075952;

Automatic exact mappings (from CISMeF team)
- Tc-99m oxidronate [Radlex concept]
Currated CISMeF NLP mapping
- technetium tc 99m hydroxydiphosphonate [MeSH concept]
- technetium tc 99m hydroxydiphosphonate [MeSH Supplementary Concept]
Semantic type(s)
- Indicator, Reagent, or Diagnostic Aid [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- technetium tc 99m hydroxydiphosphonate [MeSH Supplementary Concept]
- technetium tc 99m hydroxydiphosphonate [MeSH concept]
concept_is_in_subset
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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