Preferred Label : GITRL RNA-transfected Autologous Dendritic Cell Vaccine;
NCIt synonyms : GITRL RNA-transfected Autologous DC; GITRL RNA DC;
NCIt definition : An autologous dendritic cell (DC) cancer vaccine with potential immunostimulatory
activity. GITRL RNA-transfected autologous DC vaccine is prepared by transfecting
DCs with RNAs encoding tumor necrosis factor (ligand) superfamily, member 18 (TNFSF18
or GlTRL); expression of GlTRL results in modulating T lymphocyte survival in peripheral
tissues. Co-vaccination of this vaccine with melanoma antigen specific vaccine may
eliminate the adverse effects associated with systemic administration of immune modulators,
while also enhancing vaccine-induced immune responses.;
NCI Metathesaurus CUI : CL426029;
Origin ID : C94216;
UMLS CUI : C2986401;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
