Preferred Label : Cobalamin;
NCIt synonyms : Cobalamin (1 ); Vitamin-B12; B12 Vitamin; VIT B12;
NCIt related terms : Vitamin B12; Vitamin B-12;
NCIt definition : An essential nutrient and natural water-soluble vitamin of the B-complex family that
must combine with an intrinsic factor for absorption by the intestine, Vitamin B12
(cyanocobalamin) is necessary for hematopoiesis, neural metabolism, DNA and RNA production,
and carbohydrate, fat, and protein metabolism. B12 improves iron functions in the
metabolic cycle and assists folic acid in choline synthesis. B12 metabolism is interconnected
with that of folic acid. Vitamin B12 deficiency causes pernicious anemia, megaloblastic
anemia, and neurologic lesions.;
Alternative definition : NCI-GLOSS: A nutrient in the vitamin B complex that the body needs in small amounts
to function and stay healthy. Vitamin B12 helps make red blood cells, DNA, RNA, energy,
and tissues, and keeps nerve cells healthy. It is found in liver, meat, eggs, poultry,
shellfish, milk, and milk products. Vitamin B12 is water-soluble (can dissolve in
water) and must be taken in every day. Not enough vitamin B12 can cause certain types
of anemia (a condition in which the number of red blood cells is below normal) and
neurologic disorders. It is being studied with folate in the prevention and treatment
of some types of cancer.; CRCH: Cobalt-containing water soluble vitamin that is a coenzyme in the metabolism
of fatty acids of odd-chain length and in methyl transfer. (DRI);
UNII : 8406EY2OQA;
InChIKey : ASARMUCNOOHMLO-WLORSUFZSA-L;
CAS number : 13408-78-1;
Unit used : mcg;
Chemical formula : C62H88N13O14P.Co;
NCI Metathesaurus CUI : CL1773629;
ChEBI ID : CHEBI:28911; CHEBI:30411;
Codes from synonyms : 04086; CDR0000390323; CDR0000401508;
Origin ID : C939;
UMLS CUI : C0086024;
Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- concept_is_in_subset
