NCIt definition : A class of streptogramin-related depsipeptides isolated from the bacterium Streptomyces
virginiae and other Streptomyces bacterial species. The virginiamycins consist of
two major components, virginiamycin M1 and virginiamycin S1. These agents bind to
and inhibit ribosome assembly, thereby preventing protein synthesis. Active against
Gram-positive bacteria, these antibiotics are primarily used in veterinary practice.
(NCI04);