Vinblastine Sulfate

Preferred Label : Vinblastine Sulfate;

NCIt related terms : 29060-LE; VINCALEUKOBLASTINE; Exal; Velbe; 29060 LE; Velban;

NCIt definition : The sulfate salt of vinblastine, a natural alkaloid isolated from the plant Catharanthus roseus (Madagascar periwinkle) with antineoplastic properties. Vinblastine disrupts microtubule formation and function during mitosis and interferes with glutamic acid metabolism. (NCI04);

Alternative definition : NCI-GLOSS: A drug used with other drugs to treat several types of cancer, including advanced Hodgkin lymphoma and advanced testicular germinal-cell cancers. It is also being studied in the treatment of other types of cancer. Velban comes from the periwinkle plant Vinca rosea Linn. It blocks cell growth by stopping cell division and may kill cancer cells. It is a type of vinca alkaloid and a type of antimitotic agent.;

UNII : N00W22YO2B;

InChIKey : KDQAABAKXDWYSZ-PNYVAJAMSA-N;

CAS number : 143-67-9; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 143-67-9 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Exal; Velbe; Velban; Velsar;

Molecule name : 29060-LE;

Chemical formula : C46H58N4O9.H2O4S;

NSC code : 49842;

ChEBI ID : CHEBI:9984;

Codes from synonyms : NSC0049842; CDR0000637632; CDR0000637631; 07721;

Details

Origin ID

C931;

UMLS CUI

C0042671;

See also inter- (CISMeF)
- Vinblastine sulfate (product) [Inactive SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to NTBT
- Vinblastine (substance) [SNOMED CT concept]
- vinblastine [Substance BNPC]
- vinblastine [SNOMED Notion]
- vinblastine [MeSH concept]
- vinblastine [MeSH Descriptor]
chemical_or_drug_has_mechanism_of_action
- Microtubule Process [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_free_acid_or_base_form
- Vinblastine [NCIt concept]
has_target
- Tubulin [NCIt concept]
is_component_of_chemotherapy_regimen
- AAVD Regimen [NCIt concept]
- ABVD Regimen [NCIt concept]
- BCAVe Regimen [NCIt concept]
- Bleomycin/Dexamethasone/Lomustine/Vinblastine Regimen [NCIt concept]
- Bleomycin/Vinblastine Regimen [NCIt concept]
- CisCAII Alternating with VBIV Regimen [NCIt concept]
- Cyclophosphamide/Prednisolone/Rituximab/Vinblastine Regimen [NCIt concept]
- Dose-dense MVAC-Growth Factor Regimen [NCIt concept]
- Ganciclovir/Vinblastine Regimen [NCIt concept]
- Intralesional Vinblastine Regimen [NCIt concept]
- M-CAVI Regimen [NCIt concept]
- MVAC Regimen [NCIt concept]
- Methotrexate/Vinblastine Regimen [NCIt concept]
- N-AVD Regimen [NCIt concept]
- NOVP Regimen [NCIt concept]
- R-ABVD Regimen [NCIt concept]
- Rituximab/Vinblastine Regimen [NCIt concept]
- VABCD Regimen [NCIt concept]
- Valganciclovir/Vinblastine Regimen [NCIt concept]
- VeIP Regimen [NCIt concept]
- Vinblastine Regimen [NCIt concept]
- chlVPP Regimen [NCIt concept]
is_salt_form_of
- Vinblastine [NCIt concept]

Keyword's position in hierarchy(ies) :

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