TCL1A wt Allele

Preferred Label : TCL1A wt Allele;

NCIt synonyms : TCL1; Oncogene TCL1; TCL1 Family AKT Coactivator A wt Allele; T-Cell Leukemia/Lymphoma 1A Gene;

NCIt definition : Human TCL1A wild-type allele is located in the vicinity of 14q32.1 and is approximately 4 kb in length. This allele, which encodes T-cell leukemia/lymphoma protein 1A, plays a role in the modulation of signal transduction. Chromosomal aberrations involving the gene are associated with chronic T-cell leukemia, including translocation t(14;14)(q11;q32) which involves the T-cell receptor beta locus; and translocation t(7;14)(q35;q32) and inversion inv(14)(q11;q32) which both involve the T-cell receptor alpha/delta loci.;

GenBank Accession Number : X82240;

Details

Origin ID

C92700;

UMLS CUI

C2985257;

OMIM relation
- T-cell leukemia/lymphoma 1a [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- T-Cell Chronic Lymphocytic Leukemia [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 14q32.1 [NCIt concept]
gene_plays_role_in_process
- Protein Phosphorylation Process [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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