MTDH wt Allele

Preferred Label : MTDH wt Allele;

NCIt synonyms : LYRIC; LYRIC/3D3; AEG-1; Metadherin wt Allele; AEG1; 3D3;

NCIt definition : Human MTDH wild-type allele is located in the vicinity of 8q22.1 and is approximately 86 kb in length. This allele, which encodes protein LYRIC, plays a role in transcriptional regulation, promotion of tumor cell anchorage-independent growth and metastasis. Aberrant expression is associated with prostate cancer and hepatocellular carcinomas. Genetic variation may be associated with migraine.;

GenBank Accession Number : AF411226;

Details

Origin ID

C92659;

UMLS CUI

C2985240;

OMIM relation
- Metadherin [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 8q22.1 [NCIt concept]
gene_plays_role_in_process
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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