NCIt definition : An alkyl ester of p-hydroxybenzoic acid (PHBA) that is used most often as a preservative
in various personal care products. Parabens are active against a broad spectrum of
microorganisms and exert their activity by disrupting the integrity of the cell membrane,
causing leakage of intracellular proteins and interference with membrane transport
processes, by inhibiting synthesis of DNA and RNA or by inhibiting the activity of
certain enzymes, such as ATPases and phosphotransferases.;