Iron Isomaltoside 1000

Preferred Label : Iron Isomaltoside 1000;

NCIt definition : An intravenous colloidal solution containing trivalent iron (Fe3 ) chelated to isomaltosides, used as iron replacement. The iron in iron isomaltoside 1000 is strongly bound to the carbohydrate particles; each particle contains a trivalent iron core and a carbohydrate shell of isomaltosides which protects and stabilizes the iron core. This results in low levels of free iron and decreases inorganic, unbound iron-related toxicities thereby allowing for administration of higher doses of iron as compared to other iron-containing formulations. Upon parenteral administration and degradation of the carbohydrate shell, the iron in iron isomaltoside 1000 is released and replenishes iron stores.;

UNII : 3M6325NY1R;

CAS number : 1370654-58-2;

Drug name : Monofer;

Details

Origin ID

C92584;

UMLS CUI

C2947549;

CISMeF manual mappings
- Iron(iii) isomaltoside 1000 [SMS substance]
Currated CISMeF NLP mapping
- iron isomaltoside 1000 [MeSH concept]
- iron isomaltoside 1000 [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- iron isomaltoside 1000 [MeSH Supplementary Concept]
- iron isomaltoside 1000 [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

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