ATF1 wt Allele

Preferred Label : ATF1 wt Allele;

NCIt synonyms : TREB36; Activating Transcription Factor 1 wt Allele;

NCIt definition : Human ATF1 wild-type allele is located in the vicinity of 12q13.12 and is approximately 57 kb in length. This allele, which encodes cyclic AMP-dependent transcription factor ATF-1 protein, plays a role in transcriptional regulation. Two translocations of this gene are associated with angiomatoid fibrous histiocytoma and clear cell sarcoma. Translocation t(12;16)(q13;p11.2) with the FUS gene and t(12;22)(q13;q12) with the EWSR1 gene are expressed as fusion proteins.;

GenBank Accession Number : BC029619;

Details

Origin ID

C92178;

UMLS CUI

C2984894;

OMIM relation
- Activating transcription factor 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- Angiomatoid Fibrous Histiocytoma [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_is_element_in_pathway
- Epidermal Growth Factor Receptor Downstream Signaling Pathway [NCIt concept]
- TNF Stress Related Signaling Pathway [NCIt concept]
- p38-alpha and p38-beta Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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