Ciclopirox Olamine Lotion

Preferred Label : Ciclopirox Olamine Lotion;

NCIt synonyms : Ciclopirox;

NCIt definition : A lotion preparation of the olamine salt of ciclopirox, a synthetic hydroxypyridone derivative with broad-spectrum antifungal and anti-inflammatory activities. Although its mechanism of action is not well understood, ciclopirox may chelate trivalent cations, such as Fe3 and Al3 , thereby inhibiting the availability of essential metal co-factors for enzymes, which may result in a loss of enzyme activities that are essential for cellular metabolism, organization of cell wall structure, and other crucial cell functions in a wide variety of fungal species. This agent may also disrupt DNA repair, cell division signals and mitotic spindles as well as some elements of intracellular transport in susceptible fungi. Ciclopirox exhibits anti-inflammatory activity by inhibiting 5-lipoxygenase and cyclooxygenase (COX).;

Drug name : Loprox Lotion;

NCI Metathesaurus CUI : CL421690;

Details

Origin ID

C92171;

UMLS CUI

C2984889;

Automatic exact mappings (from CISMeF team)
- Ciclopirox [MeSH Descriptor]
- Ciclopirox (olamine) [ICD-11 Extension code]
- Ciclopirox (substance) [SNOMED CT concept]
- Product containing ciclopirox (medicinal product) [SNOMED CT concept]
- ciclopirox [SNOMED Notion]
- ciclopirox [MeSH concept]
- ciclopirox [Substance BNPC]
- ciclopirox [ATC Code]
See also inter- (CISMeF)
- ciclopirox [ATC Code]
Semantic type(s)
- Clinical Drug [UMLS semantic type]
Validated automatic mappings to NTBT
- Ciclopirox [SMS substance]
concept_is_in_subset
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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