" /> FUS wt Allele - CISMeF





Preferred Label : FUS wt Allele;

NCIt synonyms : POMP75; ALS6; Fusion Gene In Myxoid Liposarcoma Gene; HNRNPP2; Fusion (Involved In t(12;16) In Malignant Liposarcoma) Gene; TLS; Amyotrophic Lateral Sclerosis 6 Gene; Fusion, Derived From t(12;16) Malignant Liposarcoma Gene; FUS1; Fusion, Derived from 12-16 Translocation, Malignant Liposarcoma Gene; ETM4; Translocated In Liposarcoma Gene; FUS RNA Binding Protein wt Allele; Fused In Sarcoma Gene;

NCIt definition : Human FUS wild-type allele is located in the vicinity of 16p11.2 and is approximately 12 kb in length. This allele, which encodes RNA-binding protein FUS, plays a role in the maintenance of genome integrity and the regulation of both RNA processing and gene expression. Mutation of the gene is associated with angiomatoid fibrous histiocytoma and amyotrophic lateral sclerosis. Translocations of the gene are associated with malignant myxoid liposarcoma, acute myeloid leukemia and angiomatoid fibrous histiocytoma.;

GenBank Accession Number : AF071213;

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11/05/2024


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