Preferred Label : Diphtheria Toxoid/Tetanus Toxoid/Acellular Pertussis Adsorbed, Recombinant Hepatitis
B/Inactivated Poliovirus Vaccine Combined;
NCIt synonyms : Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed, Hepatitis B (Recombinant)
and Inactivated Poliovirus Vaccine;
NCIt definition : A vaccine consisting of detoxified tetanus toxoid, detoxified diphtheria toxoid, acellular
pertussis antigens, inactivated poliovirus (IPV) types 1,2 and 3 and hepatitis B (HBV)
surface antigen, with active immunizing activities against diphtheria, tetanus, pertussis,
hepatitis B, and poliomyelitis. The acellular pertussis components in this vaccine,
produced by Bordetella pertussis, are detoxified pertussis toxin (PT), filamentous
hemagglutinin (FHA) and pertactin (PRN). Upon intramuscular injection, this vaccine
activates the immune system to develop antibodies against tetanus toxin, diphtheria
toxin, B. pertussis antigens, polioviruses and HBV. The diphtheria and tetanus toxoids
and pertussis antigens (inactivated PT, FHA, and pertactin) are adsorbed onto aluminum
hydroxide; the hepatitis B antigen is adsorbed onto aluminum phosphate.;
Drug name : Pediarix;
Origin ID : C91716;
UMLS CUI : C1579315;
Semantic type(s)
concept_is_in_subset