Preferred Label : Fluorine F-18 6-Fluorodopamine;
NCIt synonyms : [18F]-6F-dopamine; [18F]-6F-DA; 1,2-Benzenediol, 4-(2-Aminoethyl)-5-(fluoro-18F)-; 3,4-Dihydroxy-6-fluorophenethylamine F-18; 18F-DA; 6-(18F)-Fluorodopamine; 18F-fluorodopamine;
NCIt related terms : Fluorine F-18 6-Fluorodopamine; 6-FLUORODOPAMINE F-18;
NCIt definition : A radioconjugate consisting of 6-fluorodopamine labeled with fluorine F18 (6-[18F]FDA),
with potential diagnostic activity. Upon administration, 6-[18F]FDA is taken up by
presynaptic sympathetic nerve endings via the norepinephrine transporter (NET) uptake-1.
Once inside, 6-[18F]FDA is rapidly converted by dopamine-beta-hydroxylase into 6-[18F]fluoronorepinephrine
(6-[18F]FNE) and stored into neuronal storage vesicles. Upon positron emission tomographic
(PET) scanning of the F18, sympathetic innervated regions can be visualized, such
as those in pheochromocytoma.;
UNII : S30483Y0LT;
InChIKey : WPKXGJXEAGYSBQ-RVRFMXCPSA-N;
CAS number : 107610-25-3;
Origin ID : C91706;
UMLS CUI : C1683281;
Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
