Preferred Label : Oncolytic Newcastle Disease Virus MTH-68H;
NCIt synonyms : Oncolytic NDV MTH-68H;
NCIt definition : An oncolytic viral agent containing the oncolytic, live-attenuated strain of the paramyxovirus
Newcastle disease virus (NDV), with potential antineoplastic activity. Upon administration,
NDV MTH-68H specifically infects and replicates in cancer cells. This may result in
a direct cytotoxic effect involving the lysis of tumor cells via apoptotic mechanisms
and may eventually lead to an inhibition of cancer cell proliferation.;
Molecule name : MTH-68H;
NCI Metathesaurus CUI : CL422080;
Origin ID : C91700;
UMLS CUI : C2984500;
Semantic type(s)
- Virus [UMLS semantic type]
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