NCIt synonyms : Squamous Cell Carcinoma of Anus; Epidermoid Anal Carcinoma; Epidermoid Carcinoma of Anus; Squamous Cell Carcinoma of the Anus; Epidermoid Carcinoma of the Anus; Squamous Cell Anal Carcinoma;
NCIt definition : A squamous cell carcinoma (SCC) arising from the anal canal or the anal margin (perianal
skin). Human papillomavirus is detected in the majority of cases. Homosexual HIV-positive
men have an increased risk of developing anal squamous cell carcinoma in comparison
to the general male population. Symptoms include anal pruritus, discomfort when sitting,
pain, change in bowel habit, and bleeding. The prognosis is generally better for anal
margin SCC than for anal canal SCC.;