Preferred Label : Leukemic Apoptotic Corpse-Pulsed Autologous Dendritic Cells;
NCIt definition : A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with
corpses of apoptotic leukemic cells, with potential immunostimulatory and antineoplastic
activities. Upon vaccination, autologous dendritic cells pulsed with leukemic apoptotic
corpse may activate the immune system to mount an anti-tumoral cytotoxic T-lymphocyte
(CTL) response against leukemic cells expressing leukemia-associated antigens, which
may result in leukemic cell lysis and inhibition of tumor cell growth. Apoptotic tumor
cell corpses contain an array of tumor associated antigens (TAAs).;
NCI Metathesaurus CUI : CL421629;
Origin ID : C91379;
UMLS CUI : C2984201;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
