Preferred Label : Alpha-fetoprotein Peptide-Pulsed Autologous Dendritic Cell Vaccine;
NCIt definition : A cell-based cancer vaccine comprised of autologous dendritic cells pulsed with four
alpha-fetoprotein (AFP) peptides, with potential immunostimulatory and antineoplastic
activities. Upon administration, AFP peptide-pulsed autologous dendritic cell vaccine
may stimulate anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against
AFP-expressing cancer cells, resulting in tumor cell lysis. AFP is overexpressed in
a variety of cancer cells.;
NCI Metathesaurus CUI : CL421594;
Origin ID : C91378;
UMLS CUI : C2984200;
Semantic type(s)
- concept_is_in_subset
