Preferred Label : Ciclopirox Olamine Oral;
NCIt definition : An aqueous suspension of the olamine salt form of ciclopirox, a synthetic, broad-spectrum
hydroxypyridone antifungal agent with additional antibacterial and anti-inflammatory
activities. Although the exact mechanism of action of ciclopirox has yet to be fully
elucidated, this agent is able to chelate trivalent cations, such as Fe3 , thereby
inhibiting the availability of essential co-factors for enzymes. This may lead to
a loss of activity of enzymes that are essential for cellular metabolism, organization
of cell wall structure and other crucial cell functions. In addition, ciclopirox exerts
its anti-inflammatory activity by inhibiting 5-lipoxygenase and cyclooxygenase (COX).;
NCI Metathesaurus CUI : CL421572;
Origin ID : C91375;
UMLS CUI : C2984197;
Semantic type(s)
- concept_is_in_subset
