PNPT1 wt Allele

Preferred Label : PNPT1 wt Allele;

NCIt synonyms : old-35; Polynucleotide Phosphorylase Gene; OLD35; 3'-5' RNA Exonuclease OLD35 Gene; PNPASE; DKFZp762K1914; Polyribonucleotide Nucleotidyltransferase 1 wt Allele;

NCIt definition : Human PNPT1 wild-type allele is located in the vicinity of 2p15 and is approximately 60 kb in length. This allele, which encodes polyribonucleotide nucleotidyltransferase 1, mitochondrial protein, plays a role in the mediation of mRNA processing and degradation and the modulation of cellular senescence.;

NCIt note : Mutation of the PNPT1 gene may be associated with melanoma.;

GenBank Accession Number : BC053660;

Details

Origin ID

C91289;

UMLS CUI

C2984134;

OMIM relation
- Polyribonucleotide nucleotidyltransferase 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 2p15 [NCIt concept]
gene_is_element_in_pathway
- Purine Metabolism Pathway [NCIt concept]
- Pyrimidine Metabolism Pathway [NCIt concept]
gene_plays_role_in_process
- Phosphorylation Process [NCIt concept]
- RNA Degradation [NCIt concept]
- RNA Processing [NCIt concept]

Keyword's position in hierarchy(ies) :

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